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Malarone (Proguanil Hydrochloride, Atovaquone)

Malarone is a highly effective malaria prevention treatment containing proguanil hydrochloride and atovaquone.

How can Malarone prevent Malaria infection?

The active ingredients in Malarone work to prevent parasites from reproducing once a person is bitten by an infected mosquito. Proguanil hydrochloride blocks the action of dihydrofolate reductase a key compound required for the parasite to reproduce. By blocking this action Malarone stops the plasmodium parasite from infecting more and more of the body’s red blood cells. Atovaquone also works by preventing successful reproduction of parasites and together these medicines provide a highly effective treatment against the Plasmodium parasite.

Order your Malarone online from Prima-Med

Dosage Information
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Quantity Price Euro Order
23 x 250mg/100mg £75.44 €89.30 Order  
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The quantity shown below is sufficient for 14 days. change

How to take Malarone for malaria prevention

Instructions on taking Malarone:

  • Once daily for two days before you go
  • Once each day you are there
  • And once a day for one week after leaving the risk area
  • Take one whole tablet, with a glass of water after a meal.

Consult your doctor 6 weeks before you travel to a tropical or sub-tropical malaria zone to discuss malaria prevention medications and any other vaccines or medicines you may need for your trip.

Malarone side effects

Some people experience side effects when taking Malarone, however most are slight or moderate. The risks associated with catching Malaria far outweigh the side effects of taking the medication.

These are the most commonly reported side effects, though many people take Malarone with no side effects at all:

  • Tummy upset
  • Vomiting
  • Fever
  • Headache
  • Mouth ulcers
  • Loss of appetite
  • Dizziness
  • Sleeping problems
  • Cough
  • Hair loss

For the full list of reported side effects, please consult the medicine’s leaflet. If you experience a side effect which is not listed on the manufacturer’s leaflet contact your prescribing doctor or a pharmacist for advice.

Malarone precautions

If you are pregnant and must travel or are taking any other medications then you need to speak to your doctor about which anti-malaria tablets are best suited to you.

If you have kidney impairment you should also ask your doctor about suitable malaria treatments

You need to complete your course of treatments correctly to benefit from the full effectiveness of Malarone. Start by taking the first tablet 1-2 days before you enter the malarial area. During your stay take one tablet everyday and then continue to take Malarone for seven days after you leave the malaria area.

It is best to take Malarone after you have eaten to avoid stomach upset.

If you are sick and vomit within one hour of taking Malarone, take another tablet as soon as possible and then continue taking the medications as instructed. You should contact your doctor for more medications when you come back, so you are still able to complete the entire course. Try not to forget to take your tablets.

Malarone is a highly effective malaria prevention medication, however there is a small chance you can still catch malaria. If you show symptoms of malaria within three months of coming back from a Malaria zone seek medical help as soon as possible. If you have intermittent flu like symptoms within a year travel consult your doctor as you may be displaying symptoms of malaria.

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